TY - JOUR T1 - Fibrin Glue and Internal Limiting Membrane Abrasion for Optic Disc Pit Maculopathy. JF - Ophthalmic Surg Lasers Imaging Retina Y1 - 2018 A1 - Almeida, David R P A1 - Chin, Eric K A1 - Arjmand, Parnian A1 - Velez, Gabriel A1 - Evans, Lucy P A1 - Mahajan, Vinit B AB -

BACKGROUND AND OBJECTIVE: To describe a novel surgical technique using pars plana vitrectomy (PPV), internal limiting membrane (ILM) abrasion, and intravitreal fibrin glue for the treatment of optic disc pit maculopathy.

PATIENTS AND METHODS: Surgical case series technique with scanning electron microscopy (SEM) of human post-mortem eyes.

RESULTS: Using SEM, the authors demonstrate the persistent adherence of vitreous fragments to the optic disc following induction of posterior vitreous detachment in human postmortem eyes. The authors describe a surgical technique using PPV, Tano Diamond Dusted Membrane Scraper for an ILM abrasion, intravitreal fibrin glue (Tisseel), and gas-air exchange to seal optic disc pits. The authors report successful long-term visual and anatomical outcomes in three patients.

CONCLUSIONS: Intravitreal fibrin glue, when combined with ILM abrasion, may be a viable treatment option for optic disc pit maculopathy with good short- and long-term visual acuity outcomes. SEM shows that ILM abrasion removes vitreous fragments, which are persistently adherent and may lead to failure with other interventional techniques. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:e271-e277.].

VL - 49 IS - 12 U1 - http://www.ncbi.nlm.nih.gov/pubmed/30566713?dopt=Abstract ER -