|Title||Fibrin Glue and Internal Limiting Membrane Abrasion for Optic Disc Pit Maculopathy.|
|Publication Type||Journal Article|
|Year of Publication||2018|
|Authors||Almeida, David R. P., Chin Eric K., Arjmand Parnian, Velez Gabriel, Evans Lucy P., and Mahajan Vinit B.|
|Journal||Ophthalmic Surg Lasers Imaging Retina|
|Date Published||2018 Dec 01|
BACKGROUND AND OBJECTIVE: To describe a novel surgical technique using pars plana vitrectomy (PPV), internal limiting membrane (ILM) abrasion, and intravitreal fibrin glue for the treatment of optic disc pit maculopathy.
PATIENTS AND METHODS: Surgical case series technique with scanning electron microscopy (SEM) of human post-mortem eyes.
RESULTS: Using SEM, the authors demonstrate the persistent adherence of vitreous fragments to the optic disc following induction of posterior vitreous detachment in human postmortem eyes. The authors describe a surgical technique using PPV, Tano Diamond Dusted Membrane Scraper for an ILM abrasion, intravitreal fibrin glue (Tisseel), and gas-air exchange to seal optic disc pits. The authors report successful long-term visual and anatomical outcomes in three patients.
CONCLUSIONS: Intravitreal fibrin glue, when combined with ILM abrasion, may be a viable treatment option for optic disc pit maculopathy with good short- and long-term visual acuity outcomes. SEM shows that ILM abrasion removes vitreous fragments, which are persistently adherent and may lead to failure with other interventional techniques. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:e271-e277.].
|Alternate Journal||Ophthalmic Surg Lasers Imaging Retina|