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Fibrin Glue and Internal Limiting Membrane Abrasion for Optic Disc Pit Maculopathy.

TitleFibrin Glue and Internal Limiting Membrane Abrasion for Optic Disc Pit Maculopathy.
Publication TypeJournal Article
Year of Publication2018
AuthorsAlmeida, David R. P., Chin Eric K., Arjmand Parnian, Velez Gabriel, Evans Lucy P., and Mahajan Vinit B.
JournalOphthalmic Surg Lasers Imaging Retina
Date Published2018 Dec 01

BACKGROUND AND OBJECTIVE: To describe a novel surgical technique using pars plana vitrectomy (PPV), internal limiting membrane (ILM) abrasion, and intravitreal fibrin glue for the treatment of optic disc pit maculopathy.

PATIENTS AND METHODS: Surgical case series technique with scanning electron microscopy (SEM) of human post-mortem eyes.

RESULTS: Using SEM, the authors demonstrate the persistent adherence of vitreous fragments to the optic disc following induction of posterior vitreous detachment in human postmortem eyes. The authors describe a surgical technique using PPV, Tano Diamond Dusted Membrane Scraper for an ILM abrasion, intravitreal fibrin glue (Tisseel), and gas-air exchange to seal optic disc pits. The authors report successful long-term visual and anatomical outcomes in three patients.

CONCLUSIONS: Intravitreal fibrin glue, when combined with ILM abrasion, may be a viable treatment option for optic disc pit maculopathy with good short- and long-term visual acuity outcomes. SEM shows that ILM abrasion removes vitreous fragments, which are persistently adherent and may lead to failure with other interventional techniques. [Ophthalmic Surg Lasers Imaging Retina. 2018;49:e271-e277.].

Alternate JournalOphthalmic Surg Lasers Imaging Retina
PubMed ID30566713