Skip to content Skip to navigation

Human Microsurgery

We use evidence-based approaches to study and improve surgery for our patients. Once surgeons and scientists have a molecular target in their sights, numerous molecular drugs are available to them. These may involve enzymes, genes, antibodies, or chemicals. Eye surgeons can precisely and safely deliver any of these molecules near specific cells in the eye, avoiding the toxicity and issues associated with drugs taken by mouth or injected into the blood stream. Once delivered, patients can be observed noninvasively in the clinic using ultra-high-resolution cameras.

Projects

A multi-institution precision health consortium for collecting ophthalmic surgical samples.

We conducted laboratory and clinical studies on macular hole repair.

We conduct studies to develop safer, more efficient surgery in patients.

Evidence-based approaches for new surgical treatments and research to discover the molecular causes.

News

Nov 7 2023 | Posted In: Press
Palo Alto, CA — Research from the Mahajan lab was featured in NIH's newsite, NIH Research Matters.
Oct 19 2023 | Posted In: 20/20 Blog
  Palo Alto, CA — The eyes may be a window into the soul, but Stanford research scientists are now showing the eyes may also be a window into overall human health. 
Aug 9 2022 | Posted In: 20/20 Blog
 
Apr 18 2022 | Posted In: 20/20 Blog
Palo Alto, CA — A Wall Street Journal article on age-related retinal tears and detachments features an interview with Stanford’s Vinit Mahajan MD, PhD, professor of ophthalmology and vice chair for
Jul 6 2021 | Posted In: 20/20 Blog
Palo Alto, CA – As genetic testing and molecular biomarkers open new avenues for medical care, researchers are more reliant on samples from human subjects than ever.

Publications

Molecular Characterization of a Rare Case of Bilateral Vitreoretinal T Cell Lymphoma through Vitreous Liquid Biopsy., Cani, Andi K., Toral Marcus A., Balikov Daniel A., Betz Bryan L., Hu Kevin, Liu Chia-Jen, Prifti Matthew V., Chinnaiyan Arul M., Tomlins Scott A., Mahajan Vinit B., et al. , Int J Mol Sci, 2021 Jun 05, Volume 22, Issue 11, (2021)
The Present and Future of Mitochondrial-Based Therapeutics for Eye Disease., Ji, Marco H., Kreymerman Alexander, Belle Kinsley, Ghiam Benjamin K., Muscat Stephanie P., Mahajan Vinit B., Enns Gregory M., Mercola Mark, and Wood Edward H. , Transl Vis Sci Technol, 2021 07 01, Volume 10, Issue 8, p.4, (2021)
Liquid biopsy proteomics of uveal melanoma reveals biomarkers associated with metastatic risk., Velez, Gabriel, Nguyen Huy V., Chemudupati Teja, Ludwig Cassie A., Toral Marcus, Reddy Sunil, Mruthyunjaya Prithvi, and Mahajan Vinit B. , Mol Cancer, 2021 02 24, Volume 20, Issue 1, p.39, (2021)
Molecular Surgery: Proteomics of a Rare Genetic Disease Gives Insight into Common Causes of Blindness., Velez, Gabriel, and Mahajan Vinit B. , iScience, 2020 Nov 20, Volume 23, Issue 11, p.101667, (2020)
Intravitreal methotrexate and fluocinolone acetonide implantation for Vogt-Koyanagi-Harada uveitis., Park, Jong G., Callaway Natalia F., Ludwig Cassie A., and Mahajan Vinit B. , Am J Ophthalmol Case Rep, 2020 Sep, Volume 19, p.100859, (2020)
Quantitative Autofluorescence Following Gene Therapy With Voretigene Neparvovec., Levi, Sarah R., Oh Jin Kyun, de Carvalho Jose Ronaldo Li, Mahajan Vinit B., Tsang Stephen H., and Sparrow Janet R. , JAMA Ophthalmol, 2020 Jun 18, (2020)