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Human Microsurgery

We use evidence-based approaches to study and improve surgery for our patients. Once surgeons and scientists have a molecular target in their sights, numerous molecular drugs are available to them. These may involve enzymes, genes, antibodies, or chemicals. Eye surgeons can precisely and safely deliver any of these molecules near specific cells in the eye, avoiding the toxicity and issues associated with drugs taken by mouth or injected into the blood stream. Once delivered, patients can be observed noninvasively in the clinic using ultra-high-resolution cameras.

Projects

A multi-institution precision health consortium for collecting ophthalmic surgical samples.

We conducted laboratory and clinical studies on macular hole repair.

We conduct studies to develop safer, more efficient surgery in patients.

Evidence-based approaches for new surgical treatments and research to discover the molecular causes.

News

Jun 15 2020 | Posted In: 20/20 Blog
Palo Alto, CA — Despite the near complete shutdown of in-person laboratory activities at the beginning of the COVID-19 pandemic, the Stanford Ophthalmology research laboratories remain incredibly productive.
May 1 2020 | Posted In: 20/20 Blog
 
Oct 16 2019 | Posted In: 20/20 Blog
Palo Alto, CA — A gene therapy clinical trial for Dry Age Related Macular Degeneration (AMD) is beginning at the Byers Eye Institute under the direction of Vinit Mahajan M.D., Ph.D., associate professor and Vice Chair for Research in Ophthalm
Oct 14 2019 | Posted In: 20/20 Blog
Palo Alto, CA – Dry macular degeneration is a common eye condition that usually occurs in people over 50. It is characterized by blurring of the central vision along with a decreased ability to see colors and fine details.
Aug 9 2019 | Posted In: 20/20 Blog
Palo Alto, CA – As the eye ages, vision problems increase, making it harder to do everyday activities. When an older patient comes in with blurred or distorted central vision, one of the causes an ophthalmologist will check for is a macular hole.

Publications

Comparison of microbiology and visual outcomes of patients undergoing small-gauge and 20-gauge vitrectomy for endophthalmitis., Almeida, David R. P., Chin Eric K., Shah Shaival S., Bakall Benjamin, Gehrs Karen M., H Boldt Culver, Russell Stephen R., Folk James C., and Mahajan Vinit B. , Clin Ophthalmol, 2016, Volume 10, p.167-72, (2016)
Management of Pediatric Aphakic Glaucoma With Vitrectomy and Tube Shunts., Elshatory, Yasser M., Gauger Elizabeth H., Kwon Young H., Alward Wallace L. M., H Boldt Culver, Russell Stephen R., and Mahajan Vinit B. , J Pediatr Ophthalmol Strabismus, 2016 Nov 01, Volume 53, Issue 6, p.339-343, (2016)
Macular Hole Closure With Internal Limiting Membrane Abrasion Technique., Mahajan, Vinit B., Chin Eric K., Tarantola Ryan M., Almeida David R. P., Somani Riz, H Boldt Culver, Folk James C., Gehrs Karen M., and Russell Stephen R. , JAMA Ophthalmol, 2015 Jun, Volume 133, Issue 6, p.635-41, (2015)
Incomplete vitreomacular traction release using intravitreal ocriplasmin., Chin, Eric K., Almeida David R. P., Sohn Elliott H., H Boldt Culver, Mahajan Vinit B., Gehrs Karen M., Russell Stephen R., and Folk James C. , Case Rep Ophthalmol, 2014 Sep-Dec, Volume 5, Issue 3, p.455-62, (2014)
Dissection of human vitreous body elements for proteomic analysis., Skeie, Jessica M., and Mahajan Vinit B. , Journal of visualized experiments : JoVE, 2011, Issue 47, (2011)