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Human Microsurgery

We use evidence-based approaches to study and improve surgery for our patients. Once surgeons and scientists have a molecular target in their sights, numerous molecular drugs are available to them. These may involve enzymes, genes, antibodies, or chemicals. Eye surgeons can precisely and safely deliver any of these molecules near specific cells in the eye, avoiding the toxicity and issues associated with drugs taken by mouth or injected into the blood stream. Once delivered, patients can be observed noninvasively in the clinic using ultra-high-resolution cameras.

Projects

A multi-institution precision health consortium for collecting ophthalmic surgical samples.

We conducted laboratory and clinical studies on macular hole repair.

We conduct studies to develop safer, more efficient surgery in patients.

Evidence-based approaches for new surgical treatments and research to discover the molecular causes.

News

Feb 13 2019 | Posted In: 20/20 Blog
Palo Alto, CA — Byers Eye Institute was recently selected to join the Foundation Fighting Blindness Consortium (FFB).
Feb 4 2019 | Posted In: 20/20 Blog
Palo Alto, CA — How can physicians and scientists make clinical trials faster, cheaper, and more likely to succeed? The answer may be proteomic analysis.
Feb 1 2019 | Posted In: 20/20 Blog
Charlotte, NC — David Almeida MD, MBA was recently featured in Retina Today's 5 Questions section.
Dec 14 2018 | Posted In: 20/20 Blog
Palo Alto, CA — Why volunteer for a clinical trial? The rigorous process of turning a new therapy into the standard of care depends on patient volunteers. 
Oct 27 2018 | Posted In: 20/20 Blog
Chicago, IL — At the American Academy of Ophthalmology meeting, Stanford ophthalmologist, Vinit Mahajan M.D., Ph.D., presented a poster detailing results on the relationship between specific patient mutations and clinical outcomes in the first FDA approved gene therapy trial in humans.

Publications

Management of Pediatric Aphakic Glaucoma With Vitrectomy and Tube Shunts., Elshatory, Yasser M., Gauger Elizabeth H., Kwon Young H., Alward Wallace L. M., H Boldt Culver, Russell Stephen R., and Mahajan Vinit B. , J Pediatr Ophthalmol Strabismus, 2016 Nov 01, Volume 53, Issue 6, p.339-343, (2016)
COMBINED VITRECTOMY AND INTRAVITREAL DEXAMETHASONE (OZURDEX) SUSTAINED-RELEASE IMPLANT., Zheng, Andrew, Chin Eric K., Almeida David R. P., Tsang Stephen H., and Mahajan Vinit B. , Retina, 2016 Nov, Volume 36, Issue 11, p.2087-2092, (2016)
Macular Hole Closure With Internal Limiting Membrane Abrasion Technique., Mahajan, Vinit B., Chin Eric K., Tarantola Ryan M., Almeida David R. P., Somani Riz, H Boldt Culver, Folk James C., Gehrs Karen M., and Russell Stephen R. , JAMA Ophthalmol, 2015 Jun, Volume 133, Issue 6, p.635-41, (2015)
Incomplete vitreomacular traction release using intravitreal ocriplasmin., Chin, Eric K., Almeida David R. P., Sohn Elliott H., H Boldt Culver, Mahajan Vinit B., Gehrs Karen M., Russell Stephen R., and Folk James C. , Case Rep Ophthalmol, 2014 Sep-Dec, Volume 5, Issue 3, p.455-62, (2014)
Dissection of human vitreous body elements for proteomic analysis., Skeie, Jessica M., and Mahajan Vinit B. , Journal of visualized experiments : JoVE, 2011, Issue 47, (2011)