Publications

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2026

Implantable ocular therapeutic systems: an insight into their clinical potential in the long-term treatment of ocular diseases   |   Kim H, Kang NW, Hong W, Abdollahramezani S, Ngo GH, Raja D, Peters O, Mahajan VB, Myung D, DeBoer C   |   Biofabrication   |   Details
Oculomics and AI: The eye as a biomarker for health span   |   Wong JLY, Cheng H, Peh WJ, Ho D, Wong TY, Hui CYY, Ting DSJ, Bee YM, Goh SY, Apte RS, Mahajan VB, Goldberg JL, Bischof E, Sinclair DA, Cheung CY, Chan HH, Fukutsu K, Tan TF, Quek CWN, Hong ASY, Jin LY, Wagner SK, Keane PA, Ferrara D, Eydelman M, Lam DSC, Wang X, Ting DSW   |   Asia Pac J Ophthalmol   |   Details
A Simplified Classification for Age-Related Macular Degeneration Based on Optical Coherence Tomography   |   Yeh TC, Lin JB, Mruthyunjaya P, Leng T, DeBoer C, Sepah YJ, Almeida DRP, Smith S, Mahajan VB   |   Ophthalmic Surg Lasers Imaging Retina   |   Details
Mitochondrial Transplantation in the Eye: A Review and Evaluation of Surgical Approaches   |   Cakir B, Yeh TC, Lin CH, Wu MR, Boilard É, Pelletier M, Singh AM, Breton Y, Patel S, Benson T, Almeida DR, Wang S, Mahajan VB   |   bioRxiv   |   Details
A novel IDS variant associated with an isolated ocular phenotype in Hunter syndrome   |   Yeh TC, Velez G, Lee SH, Ngo GH, Kumar A, Al-Moujahed A, Yu C, Leung LS, Mruthyunjaya P, Mahajan VB   |   Details
Multimodal AI fuses proteomic and EHR data for rational prioritization of protein biomarkers in diabetic retinopathy   |   Lin JB, Mataraso SJ, Chadha M, Velez G, Mruthyunjaya P, Aghaeepour N, Mahajan VB   |   Details
Gene therapy for Bietti crystalline corneoretinal dystrophy: a phase 1/2 clinical trial   |   Yang L, Xing D, Zhang J, Liu B, Jiang X, Chen S, Li W, Qu B, Qiao J, Feng X, Jia H, Hu X, Yu S, Jia R, Wang L, Mahajan VB, Dou H, Lu F, Li X   |   Mol Ther   |   Details
Oculomics and AI: The eye as a biomarker for health span   |   Le Yi Wong J, Cheng H, Peh WJ, Ho D, Wong TY, Hui CYY, Ting DSJ, Bee YM, Goh SY, Apte RS, Mahajan VB, Goldberg JL, Bischof E, Sinclair DA, Cheung CC, Chan HH, Fukutsu K, Tan TF, Quek CWN, Hong ASY, Jin LY, Wagner SK, Keane P, Ferrara D, Eydelman M, Lam DSC, Wang X, Ting DSW   |   Asia Pac J Ophthalmol   |   Details
Epidemiology of Inherited Retinal Diseases in the United States: IRIS® Registry (Intelligent Research in Sight) Analysis   |   Al-Moujahed A, Haque ME, Mahajan VB, Huckfeldt R, Pershing S   |   Ophthalmic Surg Lasers Imaging Retina   |   Details
Multi-omics liquid biopsy identifies mitochondrial dysfunction in geographic atrophy and supports the longevity-associated metabolite α-ketoglutarate as a therapeutic strategy   |   Yeh TC, Velez G, Prasad A, Lee SH, Rasmussen DK, Kumar A, Chadha M, Dabaja MZ, Singh AM, Sanislo S, Smith S, Mryuthyunjaya P, Montague A, Bassuk AG, Almeida D, Dufour A, Mahajan VB   |   medRxiv   |   Details

2025

In-clinic vitreous biopsy peel pack technique   |   Charles DeBoer, Cindy Zhao, Prithvi Mruthyunjaya, Vinit B Mahajan, Karen M Wai, Steven R Sanislo   |   International Journal Retina Vitreous   |   Details
A synthetic opsin restores vision in patients with severe retinal degeneration   |   Samarendra K Mohanty, Santosh Mahapatra, Subrata Batabyal, Michael Carlson, Gayatri Kanungo, Ananta Ayyagari, Kissaou Tchedre, Joel A Franco, Michael Singer, Samuel B Barone, Sai Chavala, Vinit B Mahajan   |   Mol Ther .   |   Details
Enhanced genotype-phenotype analysis using multimodal adaptive optics and 3D protein structure in Bietti Crystalline Dystrophy   |   Aarushi Kumar, Young Joo Sun, Ditte K Rasmussen, Aubrey Hargrave, Claudia Phillips, Jennifer T Vu, Mauricio G S Costa, Loh-Shan B Leung, Charles Yu, Alfredo Dubra, Vinit B Mahajan   |   Am J Ophthalmol Case Rep.   |   Details
Artificial intelligence's contribution to biomedical literature search: revolutionizing or complicating?   |   Rui Yip, Young Joo Sun, Alexander G Bassuk, Vinit B Mahajan   |   PLOS Digit Health   |   Details
Response: Promise and open questions of optogenetic vision restoration by MCO   |   Samarendra K Mohanty, Santosh Mahapatra, Subrata Batabyal, Michael Carlson, Gayatri Kanungo, Ananta Ayyagari, Kissaou Tchedre, Joel A Franco, Michael Singer, Samuel Barone, Sai Chavala, Vinit B Mahajan   |   Molecular Therapy   |   Details
N-terminomics and proteomics analysis of Calpain-2 reveal key proteolytic processing of metabolic and cell adhesion proteins   |   Anjali Kapilan, Mitchell Bulluss, Alexander R Ziegler, Mohamed Dabaja, Afshin Derakhshani, Anthonia Anowai, Victoria Armstrong, Rhiannon Campden, Daniel Young, Young Joo Sun, Nichollas E Scott, Laura E Edgington-Mitchell, Vinit B Mahajan, Antoine Dufour   |   Protein Science   |   Details
Unravelling CYP4V2: Clinical features, genetic insights, pathogenic mechanisms and therapeutic strategies in Bietti crystalline corneoretinal dystrophy   |   Ruixuan Jia, Shaohong Chen, Wang Li, Jinlu Zhang, Baoyuan Qu, Jing Qiao, Xiang Meng, Shicheng Yu, Xiaozhen Liu, Boling Xu, Tianjin Chen, Xiuping Shen, Wenmin Sun, Hongliang Dou, Vinit B Mahajan, Qiongjiong Zhang, Liping Yang   |   Prog Retin Eye Res   |   Details

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