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20 / 20 Blog Archive

May 14 2013 | Posted In: 20/20 Blog
Our laboratory has identified the CAPN5 gene as the cause of ADNIV, an inherited autoimmune disease of the eye. This landmark discovery represents the first identified gene that causes uveitis - a blinding inflammation within the eyes. The condition is also characterized by abnormal...
Jun 17 2012 | Posted In: 20/20 Blog
We received grant support from the Fight for Sight organization to study an inherited form of inherited retinal detachment. In this family, children develop severe retinal detachments. Our genetic analysis suggests that a novel gene variant may be the cause, and efforts to identify the variant are...
Jun 16 2012 | Posted In: 20/20 Blog
An NIH grant to study oxidative stress enzymes in the vitreous has important implications for treating diabetic vitreoretinopathy.
Jun 16 2012 | Posted In: 20/20 Blog
Endophthalmitis is a sight-threatening intraocular inflammatory disorder resulting from infection of the vitreous cavity. Following introduction of pars plana vitrectomy (PPV), the role of this treatment modality for endophthalmitis was controversial. Our laboratory is studying whether new surgical...
Jun 16 2012 | Posted In: 20/20 Blog
ADNIV is an inherited autoimmune disease of the eye. We performed a study to determine the benefit of Retisert, an implant that delivers steroids within the eye for several years. In a study published in the journal, Archives of Ophthalmology, we found that the implant inhibited specific features...

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