Publications

2026

Gene therapy for Bietti crystalline corneoretinal dystrophy: a phase 1/2 clinical trial   |   Yang L, Xing D, Zhang J, Liu B, Jiang X, Chen S, Li W, Qu B, Qiao J, Feng X, Jia H, Hu X, Yu S, Jia R, Wang L, Mahajan VB, Dou H, Lu F, Li X   |   Mol Ther   |   Details
Oculomics and AI: The eye as a biomarker for health span   |   Le Yi Wong J, Cheng H, Peh WJ, Ho D, Wong TY, Hui CYY, Ting DSJ, Bee YM, Goh SY, Apte RS, Mahajan VB, Goldberg JL, Bischof E, Sinclair DA, Cheung CC, Chan HH, Fukutsu K, Tan TF, Quek CWN, Hong ASY, Jin LY, Wagner SK, Keane P, Ferrara D, Eydelman M, Lam DSC, Wang X, Ting DSW   |   Asia Pac J Ophthalmol   |   Details
Implantable ocular therapeutic systems: an insight into their clinical potential in the long-term treatment of ocular diseases   |   Kim H, Kang NW, Hong W, Abdollahramezani S, Ngo GH, Raja D, Peters O, Mahajan VB, Myung D, DeBoer C   |   Biofabrication   |   Details

2025

Gestational hypertension increases risk of seizures in children and mice   |   Baojian Xue, Serena B Gumusoglu, Grant Tiarks, Brittany P Todd, Angela Wong, Donna A Santillan, Chin-Chi Kuo, Hsiu-Yin Chiang, Rohith Ravindranath, Sophia Y Wang, Vinit B Mahajan, Alan Kim Johnson, Heath A Davis, Polly Ferguson, Elizabeth A Newell, Mark K Santillan, Jason M Misurac, Alexander G Bassuk   |   J Clin Invest   |   Details
Discovery of a selective alpha-kinase 1 inhibitor for the rare genetic disease ROSAH syndrome   |   Jieqing Fan, Danyang Liu, Zhu Ming, Chunyu Yan, Huaixin Dang, Yanfang Pan, Xiong Wei, Zhengle Zhao, Wenzhi Wang, Shuai Zhang, Linlin Chen, Shuo Cai, Jiangbin Ke, Yaru Luo, Linjie Rao, Jingjing Chen, Zhenjie Chen, Junlin Zhou, Feixiang Chen, Xiaodi Duan, Boyue Ren, Tong-Ruei R Li, Lawrence Melvin, Jeysen Yogaratnam, Vinit B Mahajan, Hongmei Song, Henri Lichenstein, Tian Xu, Cong Xu   |   Nat Commun   |   Details
Near-Real Surgical Specimens (NRSS): A Novel Platform for Standardized Assessment of Suprachoroidal Drug Delivery   |   Vinit B Mahajan, Yoreh Barak, David R P Almeida   |   Transl Vis Sci Technol   |   Details
Safety and efficacy of MCO-010 optogenetic therapy in patients with Stargardt disease in USA (STARLIGHT): an open-label multi-center Ph2 trial   |   Byron L Lam, Vitaliy Zak Victor H Gonzalez, Ninel Z Gregori, Sai H Chavala, Subrata Batabyal, Michael Carlson, Sanghoon Kim, Ananta Ayyagari, Jean Chang, Hayley Lane, Nozhat Choudry, John Koester, Mark Von Tress, Jody Piltz-Seymour, Najam A Sharif, Stephen H Tsang, Vinit B Mahajan, David S Boyer, Allen C Ho, Samuel B Barone, Samarendra K Mohanty   |   EClinicalMedicine   |   Details
Elevated PRDM13 Disrupts Photoreceptor Function and Survival in the Mammalian Retina   |   Emily R Nettesheim, Ashley A Rowe, Tiffany Yee, Ahmed Alshaikhsalama, Tyler Cepica, Vijaya Dutt, Samita S Virani, Glen Wickersham, Vinit B Mahajan, Kent W Small, Katherine J Wert   |   Invest Ophthalmol Vis Sci   |   Details
3D Bioprinting of Cellular Therapeutic Systems in Ophthalmology: from Bioengineered Tissue to Personalized Drug Delivery   |   Hyeonji Kim, Gia-Han Ngo, Wen Hong, Soo Hyeon Lee, Vinit B Mahajan, Charles DeBoer   |   Curr Ophthalmol Rep   |   Details
Ophthalmic drug discovery and development using artificial intelligence and digital health technologies   |   Haoran Cheng, Joy Le Yi Wong, Chrystie Wan Ning Quek, Jeffrey L Goldberg, Vinit B Mahajan, Tien Yin Wong, Jodhbir S Mehta, Daniel S W Ting, Darren S J Ting   |   NPJ Digit Med   |   Details
Protocol to extract tear fluid for proteomics using Schirmer strips   |   Ngo GH, Chadha M, Sun YJ, Yu G, Lee SH, Yeh TC, Almeida DRP, Bassuk AG, Mruthyunjaya P, Dufour A, Mahajan VB   |   Star Protocol   |   Details
In-clinic vitreous biopsy peel pack technique   |   DeBoer C, Zhao C, Mruthyunjaya P, Mahajan VB, Wai KM, Sanislo SR.   |   Int J Retina Vitreous   |   Details
Automated animal gimbal steering for retinal imaging and stimulation   |   Kunala K, Ayubi GA, Franco JA, Mahajan VB, Dubra A   |   Biomed Opt Express   |   Details
In-clinic vitreous biopsy peel pack technique   |   Charles DeBoer, Cindy Zhao, Prithvi Mruthyunjaya, Vinit B Mahajan, Karen M Wai, Steven R Sanislo   |   International Journal Retina Vitreous   |   Details
Automated animal gimbal steering for retinal imaging and stimulation   |   Kunala K, Ayubi GA, Franco JA, Mahajan VB, Dubra A   |   Biomed Opt Express   |   Details
A synthetic opsin restores vision in patients with severe retinal degeneration   |   Samarendra K Mohanty, Santosh Mahapatra, Subrata Batabyal, Michael Carlson, Gayatri Kanungo, Ananta Ayyagari, Kissaou Tchedre, Joel A Franco, Michael Singer, Samuel B Barone, Sai Chavala, Vinit B Mahajan   |   Mol Ther .   |   Details
Enhanced genotype-phenotype analysis using multimodal adaptive optics and 3D protein structure in Bietti Crystalline Dystrophy   |   Aarushi Kumar, Young Joo Sun, Ditte K Rasmussen, Aubrey Hargrave, Claudia Phillips, Jennifer T Vu, Mauricio G S Costa, Loh-Shan B Leung, Charles Yu, Alfredo Dubra, Vinit B Mahajan   |   Am J Ophthalmol Case Rep.   |   Details
Artificial intelligence's contribution to biomedical literature search: revolutionizing or complicating?   |   Rui Yip, Young Joo Sun, Alexander G Bassuk, Vinit B Mahajan   |   PLOS Digit Health   |   Details
Response: Promise and open questions of optogenetic vision restoration by MCO   |   Samarendra K Mohanty, Santosh Mahapatra, Subrata Batabyal, Michael Carlson, Gayatri Kanungo, Ananta Ayyagari, Kissaou Tchedre, Joel A Franco, Michael Singer, Samuel Barone, Sai Chavala, Vinit B Mahajan   |   Molecular Therapy   |   Details
N-terminomics and proteomics analysis of Calpain-2 reveal key proteolytic processing of metabolic and cell adhesion proteins   |   Anjali Kapilan, Mitchell Bulluss, Alexander R Ziegler, Mohamed Dabaja, Afshin Derakhshani, Anthonia Anowai, Victoria Armstrong, Rhiannon Campden, Daniel Young, Young Joo Sun, Nichollas E Scott, Laura E Edgington-Mitchell, Vinit B Mahajan, Antoine Dufour   |   Protein Science   |   Details

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