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Phenomics Lab

High-throughput solutions for large-scale disease phenotyping.

We have established scalable, high-throughput phenotyping methods for characterizing human and mouse eye diseases. The mouse eye phenotype screening service is available to laboratories throughout the world. Through the development of cooperative laboratory networks, we hope to expand our screening effort.

Projects

We have established a scalable, multilevel, high-throughput phenotyping laboratory to identify mouse models for eye disease.

Capturing surgical events for careful clinical studies has always been a challenge.

News

| Posted In: 20/20 Blog
We collaborated with scientists to test software that automatically identifies fundus features of diabetic retinopathy. This technology is being commercialized with the hope of bringing eye care to underserved populations.

Publications

Evisceration of mouse vitreous and retina for proteomic analyses., Skeie, Jessica M., Tsang Stephen H., and Mahajan Vinit B. , Journal of visualized experiments : JoVE, 2011, Issue 50, (2011)
Automated early detection of diabetic retinopathy., Abràmoff, Michael D., Reinhardt Joseph M., Russell Stephen R., Folk James C., Mahajan Vinit B., Niemeijer Meindert, and Quellec Gwénolé , Ophthalmology, 2010 Jun, Volume 117, Issue 6, p.1147-54, (2010)
Connectin: a homophilic cell adhesion molecule expressed on a subset of muscles and the motoneurons that innervate them in Drosophila., Nose, A, Mahajan V B., and Goodman C S. , Cell, 1992 Aug 21, Volume 70, Issue 4, p.553-67, (1992)